Single implant placement in the maxillary aesthetic area with or without connective tissue grafting: A 1-year follow-up randomised clinical trial.

PURPOSE: To evaluate the influence of connective tissue graft on the soft tissue thickness and aesthetics around single implants placed in the aesthetic zone of the maxilla. MATERIALS AND METHODS: Forty-two patients with indications for single implant placement in the aesthetic zone were randomly allocated into two groups: the implant group (implant insertion) and the implant + connective tissue graft group (implant insertion and placement of a 1.50-mm-thick connective tissue graft). Clinical evaluations were performed at baseline, 4 months after surgery (prior to prosthetic reconstruction) and 1 year after crown placement to assess tissue thickness at the crestal aspect and the buccal aspect, buccal defects, keratinised tissue width and proximal bone resorption. Aesthetics were assessed using the pink aesthetic score index, and postoperative discomfort and pain tests were also performed. RESULTS: Only the implant + connective tissue graft group presented a significant increase in tissue thickness at the buccal aspect, with 2.36 ± 0.94 mm at baseline, 3.35 ± 1.00 mm after 4 months and 3.23 ± 0.77 mm after 1 year (P < 0.05), whereas no change was observed in the implant group. The difference between the two groups was significant after 4 months and 1 year (P < 0.05). The implant + connective tissue graft group also showed a greater reduction in buccal defects after 1 year compared to the implant group (∆ -0.50 ± 0.70 mm and ∆ -1.80 ± 1.30 mm, respectively; P < 0.05). After 1 year, a significant intergroup difference in proximal bone resorption was observed, with the implant + connective tissue graft group showing less bone resorption compared to the implant group (0.75 ± 0.20 mm and 0.92 ± 0.30 mm, respectively; P < 0.05). CONCLUSIONS: Placement of a connective tissue graft simultaneous to single implant insertion in the anterior maxillary region can increase the thickness of the peri-implant mucosa and reduce proximal bone resorption.

Eficácia de enxerto de tecido conjuntivo em pacientes que receberam implantes em áreas estéticas: um estudo longitudinal prospectivo com acompanhamento de 4 anos / Single implant placement in the maxillary aesthetic área with us without connective tissue grafting: a prospective longitudinal study with a 4-year follow-up

Os implantes osseointegrados têm sido utilizados desde a década de 50, conforme a utilização dos implantes vem crescendo, suas complicações também aumentam, principalmente quando são instalados em áreas estéticas, onde há deficiência de tecido conjuntivo peri-implantar. O objetivo deste estudo longitudinal prospectivo com 4 anos de acompanhamento foi avaliar o aumento da espessura de tecido conjuntivo peri-implantar em implantes instalados em áreas estéticas com a utilização de enxerto de tecido conjuntivo. Uma amostra de 34 indivíduos foi utilizada de um estudo prévio, o grupo teste (n=16) recebeu enxerto de tecido conjuntivo (ETC) sobre os implantes e o grupo controle (n=18) apenas o implante dental, o estudo tem um "power" de 80% (p=0,05). Após a instalação das coroas, os pacientes foram acompanhados pelo período de 4 anos, baseline, 12 meses e 48 meses, e as seguintes análises foram realizadas: Espessura tecido periimplantar vestibular (EV), deiscência óssea (DO), altura do tecido queratinizado (AQ), avaliação estética (PES/WES e Índice de Jent), avaliação estética pelo paciente (VAS), melhora da qualidade de vida (OHIP) e medidas radiográficas (COm/d). Resultados: A análise entre os grupos não foi estatisticamente significativa para as variáveis AQ, COm/d, PES/WES, Índice de Jent, estética centrada no paciente e OHIP. A análise intragrupos da COm/d foi significante em todos os períodos, tanto no teste quanto no controle. Para AQ, houve diferença no grupo controle entre o baseline e os demais períodos; na EV do grupo teste houve uma diferença significante entre o baseline e 48 meses e entre os dados de 12 e 48 meses, observando-se uma diminuição da EV, OHIP houve diferença em ambos os grupos, entre início e fim de tratamento, já as comparações entre os grupos para as variáveis EV e COm/d foram estatisticamente significante , EV apresentou maiores valores no grupo teste e Com/d menores valores no controle .Conclusão: A colocação de ETC aumenta espessura de tecido mole e após 48 meses mantem a espessura de EV, melhora DO, não aumenta AQ, não melhora a estética do ponto de vista do paciente e do profissional e a qualidade de vida não difere daqueles que receberam apenas o implante (AU)

Osseointegrated implants have been used since the mid-1950s. As the use of implants has grown, their complications also increase, especially those installed in esthetic areas, when there is a deficiency of peri-implant connective tissue. The aim of this prospective longitudinal study with 4 years of follow-up was to evaluate the increase in peri-implant connective tissue thickness in implants placed in esthetic areas using a connective tissue graft. Thrity-four patients froma previous study were divided in two groups:Test group (n=16), which received connective tissue graft (CTG) over the implants and Control group (n=18), which only the dental implant was installed. the study has a power of 80% (p=0.05). After dental crown placement, the patients were followed for a period of 4 years ( baseline, 12 months and 48 months) and the following analyzes were performed: Peri-implant tissue thickness buccal (EV), bone dehiscence (BD), height of keratinized tissue (KT), aesthetic evaluation (PES/WES and Jent Indexand by patient (VAS), quality of life (OHIP) and radiographic measurements (COm/d) Results: The analysis between groups was not significant for the variables KT, COm/d, PES/WES, Jent Index, patient-centered aesthetics and OHIP. The intragroup analysis of COm/d was significant in all periods in both test and control groups. For KT, there was a difference in the control group between the baseline and the other periods; in the EV of the test group there was a significant difference between the baseline and 48 months and between 12 and 48 months, showing a decrease in EV. In relation to OHIP, there was a difference in both groups, between baseline and 48mo.Comparisons between groups for the variables EV and COm/d were statistically significant, EV presented higher values in the test group and COm/d lower values in the control. Conclusion: CTG increased soft tissue thickness and after 48 months maintained the EV thickness, improved DO, did not increase KT, did not improve esthetics from patient's point of view neither the professional, and the quality of life did not differ from those who received only the implant (AU)

Comparison of the effects of sodium bicarbonate jet prophylaxis on blood pressure in normotensive individuals and patients with controlled hypertension: a controlled clinical trial.

This study assessed the blood pressure (BP) of normotensive subjects and subjects with pharmacologically controlled hypertension after sodium bicarbonate jet prophylaxis. Forty subjects were divided into 2 groups: a normotensive control group (n = 20) and a hypertensive group (n = 20). Blood pressure measurements were conducted at 4 timepoints: prior to the dental prophylaxis (T0), immediately after treatment (Ti), 15 minutes after treatment (T15), and 30 minutes after treatment (T30). The systolic BP (SBP) values for both groups were significantly increased at Ti (P < 0.05) and returned to their initial state at T15. Both groups also showed a significant increase in diastolic BP (DBP) values at Ti (P < 0.05); however, the basal conditions in hypertensive subjects were not restored until T30, whereas the values for normotensive subjects were restored at T15. The results indicated that systemic BP changed significantly after sodium bicarbonate jet prophylaxis in both study groups; while initial SBP values were restored by 15 minutes in both groups, the return to initial DBP values took longer in the hypertensive group than in the normotensive group.

Influência da colocação de enxerto de tecido conjuntivo ao redor de implantes em áreas estéticas: estudo clínico controlado randomizado / Influence of connective tissue graft placement around implants in esthetic areas: randomized controlled clinical trial

Os implantes dentários têm sido utilizados desde meados da década de 50, e inúmeros estudos garantem a confiabilidade para sua utilização, dessa forma o implante tem se tornado uma prática comum entre os cirurgiões dentistas. À medida que sua utilização vem crescendo, suas complicações também aumentaram, principalmente quando instalados em áreas estéticas, onde há deficiência de tecido conjuntivo perimplantar. O objetivo deste estudo clínico controlado randomizado foi avaliar o aumento do volume de tecido conjuntivo perimplantar em implantes instalados em áreas estéticas com a utilização de enxerto de tecido conjuntivo. Para este estudo, foi utilizada uma amostra de 42 indivíduos com necessidade de implantes em áreas estéticas, onde o grupo teste (n=20) recebeu enxerto de tecido conjuntivo sobre os implantes e o grupo controle (n=22) recebeu apenas o implante dental sem a colocação de enxerto de tecido conjuntivo. Para análise do aumento do tecido perimplantar foram realizadas medidas clínicas no baseline, trans-operatório e pós-operatório de 4 meses. Após 4 meses o grupo teste apresentou diferença significativa no aumento de tecido conjuntivo, uma média 3,35±1,08mm / 3,62±1,08mm na vestibular e sobre o rebordo respectivamente, quando comparado ao grupo controle 2,08±0,62mm/ 2,51±0,53mm na vestibular e sobre o rebordo respectivamente. Houve diferença significativa na diminuição da deiscência óssea vestibular para o grupo teste uma média de 0,4±0,8mm contra 1,0±0,8mm do grupo controle (p<0,05). Não houve diferença significativa quanto a dor relatada pelos pacientes e a quantidade de analgésicos ingeridos. Pode-se concluir que após 4 meses o grupo teste apresentou aumento no volume de tecido conjuntivo, diminuição da deiscência óssea vestibular e os pacientes do grupo teste não sentiram uma dor maior que o grupo controle(AU)

Dental implants have been used since 1950, and as numerous studies ensure reliability for its use, they implant have become a common practice among dentists. However , complications have also risen from its increased application, especially when they are installed in esthetic areas, where there is deficiency of periimplant soft tissue. The purpose of this randomized controlled trial was to evaluate the increase in volume periimplantar soft tissue esthetic areas with the use of connective tissue graft. Individuals in need of implants in esthetic areas were included, and divided in two groups: test group (n = 20) received a tissue graft over the implants and the control group (n = 22) received only dental implant without the connective tissue graft placement. For the analysis of periimplantar tissue augmentation, baseline, trans-operative and postoperative measurements were performed. After 4 months, the test group presented a significant difference in mean connective tissue augmentation, with 3.35 ± 1.08 mm in the vestibular area and 3.62 ± 1.08 mm on the ridge when compared to the control group, with 2.08 ± 0 62 mm in the vestibular area and 2.51 ± 0.53mm on the ridge. There was a significant difference in the reduction of vestibular bone dehiscence for the test group, with a mean of 0.4 ± 0.8 mm versus 1.0 ± 0.8 mm in the control group (p <0.05). There was no significant difference in pain reported by patients and the amount of post-operative analgesics ingested taken. It can be concluded that after 4 months the use of connective tissue graft test group resulted in an increase in connective tissue volume, decreased vestibular bone dehiscence with similar amount of postoperative pain than the control group(AU)